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["Division/Committee","Symposium Title","Control ID","Abstract Title","Author(s)","Institutions","Presentation Type","Abstract Body","Decision"]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2140680,"Metal-Mediated and Metal-Catalyzed Coupling for Incorporation of Fluorine into Aromatic Molecules","John F. Hartwig<sup>1</sup>","1. Chemistry, University of California, Berkeley, Berkeley, CA, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: Fluorine-containing aromatic compounds are widespread in medicinal chemistry and material sciences, due to their unique stability, reactivity, and biological properties. Compounds containing a fluorinated aromatic ring or a trifluoromethyl group are particularly valuable, but methods to prepare these compounds under mild conditions with broad scope have been challenging to develop. During the past several years, we have sought to exploit our expertise in the synthesis of copper complexes that are intermediates in cross coupling, our expertise in palladium-catalyzed coupling reactions, and our methods to conduct C-H bond functionalization of arenes to develop methods for the conversion of aromatic compounds to aryl fluorides and aryl fluoroalkyl compounds. This lecture will describe our results on cross coupling related to the incorporation of fluorine and fluoroalkyl groups into aromatic molecules, along with a discussion of the fundamental organometallic chemistry addressed by this methods development and the mechanisms of these new classes of reactions. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2144882,"Metal Catalyzed Carbohalogenation Reactions Through Reversible Oxidative Addition","Mark Lautens<sup>1</sup>","1. Univ of Toronto Chem Dept, Toronto, ON, Canada.  ","Oral Only : Do not consider for Sci-Mix","Abstract: Oxidative addition and reductive elimination are two fundamental steps common to many different catalytic reactions. Insertion into C-X bonds is particularly prevalent as one of the first steps in a catalytic cycle. Our research group at the University of Toronto has been exploring the synthetic potential associated with reversible oxidative addition into carbon-halogen bond and recently developed a palladium catalyzed carboiodination reaction.1 This lecture will describe the scope and limitations of the reaction2 including recent work that has expanded the scope to include carbobromination and carbochlorination. 3 1. Newman, S.G.; Lautens, M. Journal of the American Chemical Society 2011, 133, 1778-1780. 2. Petrone, D.A.; Le, C.; Newman, S.G.; Lautens, M. New Trends in Cross Coupling: Theory and Applications, RSC, Colacot, T. Ed. 2014. 3. Le, C.M.; Menzies, P.J.C.; Petrone, D.A.; Lautens, M. Angewandte Chemie International Edition 2014, 53, xxxx. doi: 201409248R1 "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2143700,"Asymmetric C-C Bond Formation in Outer Sphere Pd Catalyzed Processes","Barry M. Trost<sup>1</sup>","1. Chemistry - M/S 5080, Stanford University, Stanford, CA, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: Pd Catalyzed C-C bond forming reactions are quite unusual in the range of mechanisms by which they occur. Particularly challenging for enantioselectivity are those C-C bond forming reactions that occur outside the coordination sphere of the metal and therefore distal to the chiral ligands attached to the metal. Creation of chiral space to impose asymmetry on such processes will be discussed. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2143692,"Important Catalytic Transformations for Drug Development","Chrisantha H. Senanayake<sup>1</sup>","1. Department of Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc. , Ridgefield, CT, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: During the past two decades, the process research group at Boehrigner Ingelheim Pharmaceuticals, Inc. has been involved in the development of truly efficient, reliable, greener and economically viable catalytic and asymmetric transformations for many drugs and drug candidates. Finding effective asymmetric methodologies in a timely manner for important drug candidates has provided many advantages to producing complex APIs rapidly for clinical development. This lecture will be centered on several highlights of these methods for the synthesis of important drug candidates. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2143680,"Cross-Coupling without Redox Changes at the Metal - Enantioselective Heterodimerization of Alkenes","T. V.  RajanBabu<sup>1</sup>","1. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: One of the major challenges facing organic synthesis in the twenty first century is the utilization of abundantly available carbon sources for fine chemical synthesis. The dual problems of activation of thermodynamically stable precursors and their stereoselective incorporation pose new challenges, solutions of which may have broader implications in homogeneous catalysis, and, at a practical level, how we synthesize/manufacture chemical intermediates. In this context, we have been working on new protocols for nearly quantitative and highly selective codimerization of ethylene (and propylene), and various functionalized vinylarenes, 1,3-dienes and strained alkenes. This talk will deal with the development of various strategies for stereochemical control in enantioselective versions of these reactions using Ni(II) and Co(II) catalysts. The products of this reaction are potentially useful for the synthesis of several classes of compounds, especially with intricately placed methyl-bearing chiral centers next to a ring or at the central carbon of a skipped 1,3-diene, the latter a ubiquitous structural motif that is potentially useful for a new approach to polyketides. This chemistry can also be used to generate all-carbon quaternary centers. Applications of this chemistry for synthesis of several biologically important compounds will be discussed. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2142331,"On the Magical Power of d-Block Transition Metals as Exemplified by ZACA (Zr-Catalyzed Asymmetric Carboalumination of Alkenes) – Lipase-Catalyzed Acetylation – Transition Metal-Catalyzed Cross-Coupling for Highly Enantioselective Synthesis of Various Types of Chiral Organic Compounds","Ei-ichi Negishi<sup>1</sup>, Shiqing Xu<sup>1</sup>, Akimichi Oda<sup>1</sup>, Yohei Matsueda<sup>1</sup>, Haijun Li<sup>1</sup>, Thomas P. Bobinski<sup>1</sup>","1. H. C. Brown Laboratories of Chemistry, Purdue University, West Lafayette, IN, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: The discovery and synthetic applications of a widely applicable and highly enantioselective (>99% ee) protocol consisting of the ZACA reaction (Zr-catalyzed asymmetric carboalumination of alkenes), purification of the ZACA-products by lipase-catalyzed acetylation, and subsequent transformations, such as Pd-, Ni-, or Cu-catalyzed cross-coupling are discussed. In contrast with the Sharpless epoxidation, the Noyori hydrogenation, both of which require allylic OH substituent for satisfactory asymmetric transformations, the ZACA – Lipase-catalyzed acetylation – Cross-coupling protocol in principle requires only terminal alkenes. In practice, however, the presence of a proximal hetero-functional group can be tolerated for converting terminal alkene into a wide range of chiral organic compounds including even those displaying very feeble optical rotations, such as isotopomers, as highly pure compounds of 99.9% ee or even higher! "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2142326,"Applications of Pd and Ni catalysis to Pfizer’s portfolio.","Javier Magano<sup>1</sup>","1. MS 8156 40, Pfizer Inc, Groton, CT, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: The incorporation of Pd catalysis in the design of two commercial routes at Pfizer will be discussed. In addition, new developments in Ni catalysis research at Pfizer will be disclosed, with special emphasis on a new, stable Ni(II) precatalyst for high-throughput experimentation applications as an alternative to Ni(COD)2. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2140869,"ppm-Level Pd-Catalyzed Cross-Couplings in Water at Room Temperature","Bruce H. Lipshutz<sup>1</sup>","1. Dept of Chem  Biochem, Univ of California, Santa Barbara, CA, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: Several Pd-catalyzed cross-coupling reactions will be presented that can now be effected not only in water at RT,1 but in the presence of ppm levels of an inexpensive source of Pd. A new ligand that leverages high substrate/catalyst concentrations found in aqueous nanomicelles, derived from either designer surfactant TPGS-750-M or Nok, is the key to these advances. References 1. Reviews: Lipshutz, B. H.; Ghorai, S. Green Chem. 2014, 16, 3660; Lipshutz, B. H.; Isley, N. A.; Fennewald, J. C.; Slack, E. D. Angew. Chem., Int. Ed. 2013, 52, 10952; Lipshutz, B. H.; Ghorai, S. Aldrichimica Acta, 2012, 45, 3; Lipshutz, B. H. Platinum Metal Reviews, 2012, 56, 62; Lipshutz, B. H.; Ghorai, S. Aldrichimica Acta, 2008, 41, 59. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2140704,"Carbon-carbon and carbon-heteroatom bond forming reactions in continuous flow","Timothy Noël<sup>1</sup>","1. Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, Eindhoven, Netherlands.  ","Oral Only : Do not consider for Sci-Mix","Abstract: The use of microfluidic devices has recently attracted much attention from the pharmaceutical industry.[1] This is due to the fact that these devices provide several advantages for chemical synthesis, such as enhanced heat- and mass-transfer, precise control over residence (reaction) time and scalability. In recent years, our group has been focused on the development of more efficient cross-coupling, C–H activation and photocatalytic reactions to establish carbon-carbon and carbon-heteroatom bonds. This lecture will describe our results in this field and will provide insight information about the discovery process and the different parameters that led to success. [1] T. Noël, V. Hessel, in New trends in cross-coupling: Theory and applications, T. J. Colacot Ed., RSC Catalysis series No. 21, 2015, pp 610-644. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2140689,"Photoinduced, Copper-Catalyzed Coupling Reaction","Gregory C. Fu<sup>1</sup>","1. 201B Schlinger Lab MC 101-20, California Inst of Technology Chem  Chem Eng, Pasadena, CA, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: The Ullmann reaction to form C–N bonds, first described over a century ago, is now a classic method in organic synthesis. During the time since its discovery, there had been no reports of a photoinduced variant. Instead, copper-mediated and copper-catalyzed processes have generally been effected with the aid of heat (e.g., at 60–120 °C). Recently, we have established that a photoinduced Ullmann C–N arylation can proceed at a temperature as low as –40 °C. The reaction of an amine with an alkyl halide is a classic “textbook” approach to C–N bond construction. For efficient C–N bond formation, the electrophile should generally be a good substrate for an SN2 reaction. A mild, transition metal-catalyzed N-alkylation that proceeds through a radical pathway for C–X cleavage has the potential to address important limitations of the classic SN2 approach. In this lecture, recent efforts to address this challenge will be described. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2140683,"Understanding and Design of Organopalladium Reactivity with Experimental and Computational Tools","Franziska Schoenebeck<sup>1</sup>","1. RWTH Aachen, Aachen, Germany.  ","Oral Only : Do not consider for Sci-Mix","Abstract: Detailed understanding of catalytic transformations is key to designing better catalysts. This talk will give insights on case studies and reactivity designs recently undertaken in our laboratory. A combination of experimental and computational tools were applied to study and/or predict the favored reaction mechanisms, active catalytic species, ligand and additive effects of selected transformations mediated by palladium species of the oxidation states 0, I, II and III.1 A particular emphasis will be made on the oxidation state I. As a result of these investigations, novel reactivities have been uncovered. (1) For a recent review, see: Bonney, K. J.; Schoenebeck, F. Chem. Soc. Rev. 2014, 43, 6609. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2146826,"Connecting Directed ortho Metalation – Transition Metal Catalyzed Chemistries","Victor A. Snieckus<sup>1</sup>","1. Dept Chemistry, Queens University, Kingston, ON, Canada.  ","Oral Only : Do not consider for Sci-Mix","Abstract: The common theme in our laboratories at Queen’s University is the discovery and development of new DoM aromatic/heteroaromatic chemistry, separate and linked to transition metal catalyzed processes, and their demonstration in bioactive molecule, natural product, and materials construction. A selection of these themes, including recent departures into DMG dances and Ir- and Ru-catalyzed DoM-enhancing links, will be described. "]
["[BMGT] Division of Business Development & Management ","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",2144345,"The Story of Pd-Catalyzed Coupling: The Reactions of the 21st Century","Thomas Colacot<sup>1</sup>","1. Johnson Matthey Catalysis and Chiral Technologies, West Deptford, NJ, United States.  ","Oral Only : Do not consider for Sci-Mix","Abstract: Pd-catalyzed cross-coupling reactions have become integral to both academia and industry over that last two decades, although the seminal contributions happed during the 1970’s. These reactions constitute one of the most powerful methods for the formation of C-C and C-heteroatom bonds with direct applications in the synthesis of pharmaceuticals, agrochemicals, materials for electronic devices, and more. At Johnson Matthey, our goal has long been to provide practical yet novel catalysts for these applications on commercial scale, while providing a theoretical understanding behind the structure activity relationship. In this regard, we have developed and introduced many exceptional precatalysts (traditional and new-generation) for several reaction types including Heck, Suzuki-Miyaura, ketone enolate arylation, Sonogashira, Buchwald-Hartwig amination, to name a few for commercial applications. Herein, we will cover the history of the development and implementation of these catalysts from an industrial perspective while understanding the role of academia, covering the past two decades. "]

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["Symposia Code","Symposia Title","Session Code","Session Title","Type","Expected Attendance","Organizer","Organizer Email","Organizer 2","Organizer 2 Email","Organizer 3","Organizer 3 Email","Presider","Presider Email","Presider 2","Presider 2 Email","Newsworthy","Newsworthy Reason","Co-sponsor - Cooperative","Co-sponsor - Nominal","Co-sponsor - Financial","AM/PM/EVE","Session Track","Start Time","Date","Duration"]
["BMGT001","ACS Award in Industrial Chemistry: Symposium in Honor of Thomas J. Colacot - Invited - Oral",null,null,"Oral"]

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["BMGT001"]

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["PRES: Presidential Event"]
["MPPG: Multidisciplinary Program Planning Group"]
["AEI: Academic Employment Initiative"]
["AGFD: Division of Agricultural and Food Chemistry"]
["AGRO: Division of Agrochemicals"]
["ANYL: Division of Analytical Chemistry"]
["BIOT: Division of Biochemical Technology"]
["BIOL: Division of Biological Chemistry"]
["BMGT: Division of Business Development and Management"]
["CARB: Division of Carbohydrate Chemistry"]
["CATL: Division of Catalysis Science and Technology"]
["CELL: Division of Cellulose and Renewable Materials"]
["CHED: Division of Chemical Education"]
["CHAL: Division of Chemistry and the Law"]
["CHAS: Division of Chemical Health and Safety"]
["CINF: Division of Chemical Information"]
["TOXI: Division of Chemical Toxicology"]
["COLL: Division of Colloid and Surface Chemistry"]
["COMP: Division of Computers in Chemistry"]
["ENFL: Division of Energy and Fuels"]
["ENVR: Division of Environmental Chemistry"]
["FLUO: Division of Fluorine Chemistry"]
["GEOC: Division of Geochemistry"]
["HIST: Division of the History of Chemistry"]
["I&EC: Division of Industrial and Engineering Chemistry"]
["INOR: Division of Inorganic Chemistry"]
["MEDI: Division of Medicinal Chemistry"]
["NUCL: Division of Nuclear Chemistry and Technology"]
["ORGN: Division of Organic Chemistry"]
["PHYS: Division of Physical Chemistry"]
["POLY: Division of Polymer Chemistry"]
["PMSE: Division of Polymeric Materials Science and Engineering"]
["PROF: Division of Professional Relations"]
["RUBB: Rubber Division"]
["SCHB: Division of Small Chemical Businesses"]
["CCS: Committee on Chemical Safety"]
["CCPA: Committee on Chemistry and Public Affairs"]
["CWD: Committee on Chemists with Disabilities"]
["CCA: Committee on Community Activities"]
["CORP: Committee on Corporation Associates"]
["D&I: Diversity and Inclusion Advisory Board"]
["DAC: Committee on Divisional Activities"]
["CEPA: Committee on Economic and Professional Affairs"]
["CEI: Committee on Environmental Improvement"]
["ETHC: Committee on Ethics"]
["G&A: Grants and Awards Committee"]
["IAC: International Activities Committee"]
["LAB: Leadership Advisory Board"]
["LSAC: Committee on Local Section Activities"]
["CMA: Committee on Minority Affairs"]
["NTS: Committee on Nomenclature, Terminology and Symbols"]
["CPT: Committee on Professional Training"]
["CPS: Committee on Project SEED"]
["COMSCI: Committee on Science"]
["SCC: Senior Chemists Committee"]
["SOCED: Society Committee on Education"]
["CTA: Committee on Technician Affairs"]
["WCC: Women Chemists Committee"]
["YCC: Younger Chemists Committee"]
["BTEC: Biotechnology Secretariat"]
["MACR: Macromolecular Secretariat"]

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["Concluding Remarks"]
["Discussion"]
["Introductory Remarks"]
["Intermission"]
["Panel Discussion"]