Name:
Pierre Matricon
Country:
Sweden
City:
Uppsala
State/Province:
ACS Member:
true
Local Section:
International Chapter:
Technical Division Membership:
Biological Chemistry Division,Medicinal Chemistry Division,Organic Chemistry Division,Carbohydrate Chemistry Division,Catalysis Science and Technology
Technical Division Membership Emeritus:
Subdivision Member:
ACS Activities:
Company/Institution Name:
Career Stage:
Retired
Research and Special Interests:
As a graduate student, I am really passionate about the molecular recognition processes in life sciences. I would like to access a research career in Computer-Aided Ligand Design for various innovative applications such as Drug Vectorization (e.g. Targeting specific overexpressed cell receptors or cell compartments (using localization signal mimetics)), Peptidomimetics as Protein-Protein Interactions inhibitors, Protein Epitope Mimetics (as vaccines), Aptamers and Gene Silencing (siRNAs).
For these kinds of studies, I would be interested in using several methods of interest as those from Cheminformatics (Fragment-based, Combinatorial Libraries Design, Fingerprinting, (3D)-QSAR, Pharmacophore Modeling, Diverse Set Selection and Similarity-Based Targeted Chemical Space Exploring), Protein-Ligand and Protein-Protein Docking Methods (Hot-Spots Prediction for Structure-based and Important Fragments Identification for the Design of Peptidomimetics), Molecular Modeling and Homology Modelling.
Area of Expertise:
Drug Design, Cheminformatics and Molecular Modeling
Years of Expertise: