Chelation is the current treatment for lead poisoning. Different chelating agents have been evaluated in many researches. meso-2, 3-dimercapto-succinic acid (DMSA)is reported as one of the most suitable ligands for being used in the Pb(II) poisoning therapy because of their high effectiveness and low toxicity. Sodium 2,3-dimercaptopropanesulfonate (DMPS) has been used in a study to assess its use as an antidote against non-metallic pesticides as nereistoxin insecticides. It has also been noted in a review of existing chelating agents for the treatment of heavy metals and metalloid intoxication. Detoxification of heavy metal.
DMSA itself is a very well known organic molecule that is widely used as a chelating agent for treating lead poisoning. It is also one of the most promising chelating agents in the pharmaceutical industry. Studies of DMSA in the context of nanoscience are also growing significantly because of its versatility in terms of binding to the surfaces of nanoparticles (NPs).