Name:
Bolin Geng
Country:
United States
City:
Andover
State/Province:
MA
ACS Member:
false
Local Section:
Northeastern
International Chapter:
Technical Division Membership:
Medicinal Chemistry Division
Technical Division Membership Emeritus:
Subdivision Member:
ACS Activities:
Company/Institution Name:
Career Stage:
Professional
Research and Special Interests:
Experiences in discovery medicinal chemistry programs in anti-infectives, oncology, immunology and CNS areas. Multi-step synthesis design and execution. Competitive IP analysis. logical SAR development to address thorny discovery issues in Hit to Lead and Lead Optimization programs. Pragmatic integration of DMPK and toxicological data in late stage drug discovery projects. CRO management.
Area of Expertise:
Organic Chemistry, Medicinal Chemistry, Combinatorial Chemistry, Drug Discovery, Hit-to-Lead, Lead Optimization. SBDD, Chemoinformatics tools.Publications: Bioorg. Med. Chem. Lett. 2011, 21, 5432-5435; Bioorg. Med. Chem. Lett. 2009, 19, 930-936 Bioorg. Med. Chem. Lett. 2008, 18, 6100-6103 Bioorg. Med. Chem. Lett. 2008, 18, 4368-4372 C&EN News, 2006, 84, 2-3 Antimicrob. Agents Chemother. 2004, 48, 1541-1547 Bioorg. Med. Chem. Lett. 2002, 12, 775-778 J. Med. Chem. 1997, 40, 3423-3433 Bioorg. Med.Chem. Lett. 1995, 5, 1513-1518 Organometallics, 1995, 14, 3112-3115 Tetrahedron Lett. 1994, 35, 985-988 Tetrahedron, 1993, 49, 4603-4618 J. Org. Chem. 1993, 58, 1443-1448 Organometallics, 1993, 12, 2478-2486 Bull. Soc. Chim. Fr. 1993, 130, 273-280 J. Chem. Soc., Chem. Comm. 1991, 211-213 Tetrahedron Lett. 1991, 32, 4121-4124 Gaodeng Xuexiao Huaxue Xuebao, 1988, 9, 234-238 Chemical Research in Chinese Universities, 1988, 4, 61-66;
Years of Expertise:
16-20