Name:
Geetali Pachauri
Country:
IND
City:
Varanasi
State/Province:
ACS Member:
Member
Local Section:
International Chapter:
Z704,India
Technical Division Membership:
D521,Organic Chemistry Division
Technical Division Membership Emeritus:
Subdivision Member:
ACS Activities:
Company/Institution Name:
Career Stage:
Professional
Research and Special Interests:
July"08- till date: EnEm Nostrum Remedies Pvt. Ltd. (a division of Nostrum LLC) (US based MNC), Mumbai, India
Principal Scientist & Group Leader (Pharmaceutical Research & Development)
Main Roles and Responsibilities
Actively involved new establishment of new R&D center with full equipped advanced modern analytical instruments ie BRUKER BIOSPIN Advance 400 Ultra Shield NMR with BBO probe, Agilent LC MS, Combi- flesh, preparative HPLC, Agilent HPLC, fully involved in purchasing of capital items.
Initiated chemical work in new established labs with procurement of all lab glass ware and general inventory.
Established the route for Sodium Stibogluconate (Pantostam) (chiral molecule) and made in m grams.
Working on Cimetropium Bromide ( Antispasmodic ) by NI (stereo-specific) route and resolution of Tropic acid by diasteriomeric resolution to get S-tropic acid.
Working of Paliperidone (antipsychotic drug) by NI route.
Mar"07- 08: Sterling Biotech Limited, Vadodara, India.
Manager (Process Development and Mfg)
Main Roles and Responsibilities
Spearheading a team of scientists involving 4 M.Sc. and 2 Ph.D.
Actively involved new establishment of synthetic and ADL labs inclusive XRPD installation on site.
Developed industrial viable process for bottle-neck intermediate (Chiral molecule) of Palonosetron. HCl with cost optimization effectively and establishing impurity profile of Coenzyme Q10 by H-NMR, C13-NMR and LC-MS techniques.
May"06 to Feb"07: Syngenta Research and Technology Centre, Goa, India.
Team Leader - Research Synthesis
Main Roles and Responsibilities
Pioneered a team of 5 M.Sc. and 1 Ph.D Scientists.
Synthesized different Molo and Di- substituted naphthnols, quinolinols, isoquinolinols , advanced intermediates of final products through innovative routes
Synthesized final peptide based agro-compounds in desired quantity and purity within stipulated time and dispatched them to Basel and UK RNT Labs.
The Attainments
Attended sixty days training programme in Basel, Switzerland and Jeolott"s Hill,London, UK.
Projects initiation with collaboration of Swiss and UK based RND Scientists.
Net conferencing regularly to carry forward assigned lead finding and lead optimization projects with R&T Goa, Basel, Jeolott"s Hill Centers.
Agrochemical Design Concept: Seminar, headed by Dr. Steve Smith/ Mike Robson; 26th May 2006; At Jeolott"s Hill Syngenta International Research Centre, Bracknell, Berkshire, RG 42 6 EY, United Kingdom.
Discovery of Agrochemicals: Seminar , headed by Dr. Steve Smith/ Mike Robson ; 5th June 2006; At Jeolott"s Hill Syngenta International Research Centre, Bracknell, Berkshire, RG 42 6 EY, UK.
Advanced Information & Technology for Scientific documentation: at Syngenta Crop Protection, Basel, Switzerland. May 2006
Intercultural Awareness: How to become an effective Global Performer at Jeolott"s Hill Syngenta International Research Centre, Bracknell, Berkshire, RG 42 6 EY, United Kingdom. June 2006.
Safety of People and the Environment (HSE) Program: at Syngenta Crop Protection, Basel, Switzerland. 29th May 13th June 2006; At Jeolott"s Hill Syngenta International Research Centre, Bracknell, Berkshire, RG 42 6 EY, United Kingdom.
May"05 to Apr"06: Neuland laboratories Limited, Hyderabad
Dy. Manager (Research & Development)
Main Roles & Responsibilities
Directing a team of 6 experienced Scientists.
Entrusted with the responsibility of developing:
o Azabicyclo nonane ( Mox
Area of Expertise:
o Adept in Basic Research, generic research, process development of APIs & its intermediates.
o Gathered vast Experience in product isolation & purification through various techniques i.e. column, flash master chromatography, pre-TLC, crystallization and re-crystallization.
o Sound knowledge of carrying out organic reactions in milligram to multi-grams batches of synthetic chemistry/natural products using cGLP and cGMP norms with HSE guidelines.
o Experience in lipid chemistry, lipid analysis, wet chemistry & interpretation of analytical data of molecules using modern instrumental techniques i.e. UV-Vis, IR, XRPD, NMR (H1, C13), Mass Spectrometry, TLC, Prep- TLC, MPLC, HPLC, Prep- HPLC, GC, headspace GC, GC/MS-MS, LC /(MS)n.
o Highly skilled in reaction optimization, process improvement, prompt redressal of trouble shootings and cost optimization.
o Managed gamut of tasks including planning, budgeting and costing of projects and execution there of.
o Literature search with conventional, electronic methods, SciFinder, cross fire & computer basics.
o Identification of possible synthetic routes through patent search.
o Handling projects independently & spearheading a team of scientists.
o Demonstrated excellent communication skills with cross-functional national and international R&D team
Years of Expertise:
6-10