Name:
Frank Li
Country:
United States
City:
San Francisco
State/Province:
CA
ACS Member:
false
Local Section:
California
International Chapter:
Technical Division Membership:
Technical Division Membership Emeritus:
Subdivision Member:
ACS Activities:
Company/Institution Name:
Career Stage:
Professional
Research and Special Interests:
• Develop new Mass Spectrometry methods for characterizing post-translational modifications on histons
• Develop analytical separation methods for separating histone isomers generated by many modifications
• Develop new mass spectrometry based strategies for system biology
Area of Expertise:
• Hands-on experience on Protein/Peptide Identification by ESI/MS
• Hands-on experience on Post-translational Modification Characterization by bottom-up (enzymatic digestion plus nano ESI/LC/MS/MS) and top-down Mass Spectrometry(ESI/LC/ECD/FTICR/MS/MS)
• Proficient in analytical separation method development by CE and HPLC
• Five-year experience on analytical instrumentation method development for high throughput separation and sensitive detection of protein and small molecules by capillary electrophoresis (CE)
• Hands-on experience on protein characterization by Mass Spectrometry, SDS-PAGE, SDS-CGE, IEF, UV/Vis, Fluorescence Spectroscopy
• Extensive research experience on X-ray Crystallography for protein structure determination
Years of Expertise:
16-20