John Garner

Chitosan-Fluorescein used for investigating targeted muco-adhesive drug-delivery to fish

Blog Post created by John Garner on Dec 3, 2015

Chitosan is a readily available biomaterial chemically derived from chitin which comprises crab-shells and other biological sources. This amino-polysaccharide has many interesting properties including biodegradability, biocompatibility, an inherent resistance towards bacteria, and muco-adhesion. Recently, researchers in Brazil utilized Fluorescein conjugated chitosan to track nanoparticles as they utilized them for delivery of medicines to fish in order to minimize aquatic disease. Similar, fluorescently conjugated chitosans, are available from PolySciTech division of Akina, Inc under the Kitopure brand line (https://akinainc.com/polyscitech/products/Kitopure/index.php, e.g. Kito-8 and Kito-9).  Read more about the recent aquatic drug-delivery research here: Costa, AC da S., H. M. Brandao, S. R. Silva, A. R. BentesSousa, J. A. P. Diniz, J. de J. Viana Pinheiro, M. de FC Melo, J. O. C. Silva, E. R. Matos, and R. M. RibeiroCosta. "Mucoadhesive nanoparticles: a new perspective for fish drug application." Journal of fish diseases (2015). http://onlinelibrary.wiley.com/doi/10.1111/jfd.12373/full

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