Pharmaceutical Chemists

While developing and formulating micronutrient supplements into effervescent tablets, what preparation methods can be used? ... View more

According to scientific paper, various chemotherapeutic agents are used to treat the breast cancer, such as letrozole, anastrozole, exemestane, goserelin, leuprorelin, etc. Among the plenty of APIs, tamoxifen citrate is a nonsteroidal weak estrogen that has found successful applications for each stage of breast cancer in the treatment of selected patients. I need to know more details. ... View more

Moxifloxacin hydrochloride is a crystalline powder which is soluble in DMSO (dimethyl sulfoxide) and dimethyl formamide. Moxifloxacin hydrochloride is an 8-methoxy-fluoroquinone compound with broad-spectrum bactericidal activity against gram-positive strains (including Corynebacterium species, Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus warneri, Streptococcus pneumoniae, and Streptococcus viridans group) and gram-negative strains (Acinetobacter lwoffii, Haemophilus influenzae, and Haemophilus parainfluenzae). ... View more

Microbial safety must be considered at all stages of the development, manufacturing, and subsequent storage and use of the drugs. The microbial limit test (MLT) can evaluate how many specific microorganisms are present in non-sterile pharmaceutical samples from raw materials to final products, the test can determine if certain microorganisms are exceeded quantitative limits.  ... View more

Hello, I am a website creator working on a site about therapeutic properties of chemical compounds found in essential oils and I need a recommendation for a book or a resource about information on this. The quoted info below I found on Wikipedia, it is helpful but the information on different plants is not consistent. With some plants there isn´t even mention of therapeutic properties of the chemical compounds, that´s why I need a book, dictionary or online reliable resource. from Wikipedia: "Medical use and pharmacology Chemical compounds present within chamomile have demonstrated the ability to bind GABA receptors, modulate monoamine neurotransmission, and have displayed neuroendocrine effects.[8] Major chemical compounds present within chamomile include apigenin and alpha-bisabolol.[2][8] There is Level B evidence to support the claim that chamomile possesses anxiolytic (anti-anxiety) properties and chamomile may have clinical applications in the treatment of stress and insomnia.[8] Other classes of chemical compounds found within the chamomile plant include: sesquiterpenes, terpenoids, flavonoids, coumarins such as herniarin and umbelliferone, phenylpropanoids such as chlorogenic acid and caffeic acid, flavones such as apigenin and luteolin, flavanols such as quercetin and rutin, and polyacetylenes.[2][9] Alpha-bisabolol has been shown to have antiseptic properties, anti-inflammatory properties, and has also been demonstrated to reduce pepsin secretion without altering secretion of stomach acid.[9] Umbelliferone has been shown to be fungistatic.[9]Apigenin has demonstrated strong chemopreventive effects.[10] Coumarin compounds present in chamomile such as herniarin and umbelliferone may have blood thinning properties and there is some evidence that chamomile may interact with other medications causing drug-drug interactions.[6] Chamomile has been used for inflammation associated with hemorrhoids when applied topically.[9] Chemical components of chamomile extract have demonstrated anti-inflammatory,[2][4] antihyperglycemic,[2] antigenotoxic,[11] and anticancer properties[2] when examined in vitro and in animal studies.[12]" Also information related to therapeutic properties on these would be helpful: Oxigenated compounds: Alcohols: Monoterpene alcohols Sesquiterpene alcohols Phenols: Oxides: Esthers: Ethers: Aldehydes: Ketones: Lactones and coumarins: Terpene Hydrocarbons Monoterpene hydrocarbons: Sesquiterpenes: I rather have the information aimed to the lay person if possible, but that a more scientific mind would find admisible. like a middle ground. Thank you so much in advance, sorry for making you read so much. I tried to be as succinct as possible. Aliyah Nahyhu. ... View more