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Medroxyprogesterone

Question asked by Farzana Shahrin on Oct 31, 2019

Hi, I have a question regarding my university assignment. In this case; it’s medroxyprogesterone. We all know that it’s a hydrophobic drug, hence, we are assigned to create a sterile injection in aqueous formulation. Aqueous means it has to be solubilized in water, but, the problem here is, medroxyprogesterone is poorly-water soluble but is really soluble in chloroform. So, I just wanna discuss about it here. How do we make it to be soluble in water (is it possible to do it so?) Thank you. And the questions below (the handwritten ones) I hope you can explain that also, theyre the things we have to present.. Help me, thank you!

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