NIH Funding Opportunities from NIH Countermeasures Against Chemical Threats (CounterACT) Program

Discussion created by DYeung on Mar 28, 2011
Latest reply on Aug 4, 2011 by DYeung

Within the Department of Health and Human Services (HHS), the NIH has  taken a leadership role in pursuing the development of new and improved  medical countermeasures (to include alternative routes of delivery of  existing therapeutics) designed to prevent, diagnose, and treat the  conditions caused by potential and existing chemical agents of terrorism  (e.g. toxins targeting the eyes, skin, metabolic pathway, neurological,  and pulmonary systems). In addition, many of the same chemicals posing a  threat as terrorist agents may also be released from transportation and  storage facilities by industrial accidents or during a natural  disaster.

The NIH has developed a comprehensive Countermeasures Against Chemical  Threats (CounterACT) Research Network that includes Research Centers of  Excellence, individual research projects, SBIRs, contracts and other  programs. This trans-NIH CounterACT network conducts basic,  translational, and clinical research aimed at the discovery and/or  identification of better therapeutic medical countermeasures against  chemical threat agents, and facilitates their movement through the  regulatory process. The overarching goal of this research program is to  enhance our medical response capabilities during an emergency.

Agents of interest include (but not limited to): methyl mercury, methyl  isocyanate, cyanide, phosgene, chlorine, sulfur/nitrogen mustard,  Lewisite, neurotoxic OP pesticides (e.g. parathion, chlorpyrifos, etc),  chemical warfare agents. Scope of research may include identification of  new or existing therapeutics that can treat victims of a chemical  emergency, model development, biomarker identification to guide  therapeutic intervention, modeling of long-term sequelae from a single  acute exposure incident, alternative route of administration of  currently available drugs to enable use in a mass casualty scenario,  etc.


For more information, including active funding opportunity announcements, see:  www.ninds.nih.gov/counteract