3 Replies Latest reply on Jun 29, 2011 8:14 AM by Thomas Spratt

    ACS Meeting in Denver, the TOXI Program

    Thomas Spratt

      Post questions and comments about the TOXI program at the ACS meeting in Denver here.

        • Re: ACS Meeting in Denver, the TOXI Program
          Shana Sturla

          Dr. Robert J. Kavlock of the US EPA will be a special guest of the division at the National ACS meeting and will deliver a keynote address that offers his perspectives as Director of the National Center for Computational Toxicology within EPAs Office of Research and Development.  Prior to this position, Dr. Kavlock spent 15 years as the Director of the Reproductive Toxicology Division in NHEERL/ORD.


          Dr. Kavlock’s presentation will enhance the ACS meeting theme of “Chemistry of Air, Space and Water” within the TOXI framework of “Human Exposure and Responses to Toxins from the Air and Water.”  In addition, TOXI will host two special symposia within this framework, including the Monday afternoon session concerning Arsenic Metabolism and the Wednesday morning session concerning Endocrine Disruptors.  Dr. Kavlock’s talk will round out the program on Monday afternoon.

          • Re: ACS Meeting in Denver, the TOXI Program
            Thomas Spratt

            Division of Chemical Toxicology Travel Awards

            242ndNational Meeting of the American Chemical Society in

            Denver, Colorado:August 28-September 1, 2011

            ApplicationDeadline:  June 17, 2010


            The Division of Chemical Toxicology will award travel grants (maximum $750) forparticipation in the 242nd National Meeting of the American ChemicalSociety, in Denver, Colorado.  Travelaward funds should be utilized for the reimbursement of coach transportationand hotel costs (receipts required).  

            All students and postdoctoral fellows who are active members or affiliates of the Division of Chemical Toxicology are eligible to apply. 

            To applyfor a Travel Award


            In a single PDF document please compile thefollowing information:


            (1)      A completed “Travel Award Application” (see attached Word document).

            (2)      A printed copy of the abstract submitted for acceptance to this meeting.

            (3)      A onepage CV

            (4)      A signed letter of support from your faculty advisor.


            This compiled document should be sent as ONE PDF FILE as a single EMAIL attachmentto:




            Be sure to use the subject line "ACS Chemical Toxicology Travel Award" for your electronic application.

            • Re: ACS Meeting in Denver, the TOXI Program
              Thomas Spratt

              Dave Thomas, an organizer for the Human Exposure and Responses to Toxins from the Air and Water  (Monday 1:30 PM -3:45 PM) wrote a short synopsis of the symposium


              A session entitled "Human Exposure and Responses to Toxins from the Air and Water: Arsenic Metabolism and Health Effects" has been organized for 242nd meeting of the American Chemical Society.  This session will feature three presentations focused on current studies of arsenic toxicity.  Arsenic contaminates drinking water supplies worldwide; thus, millions of individuals are dependent on arsenic-contaminated water sources.  Studies in exposed populations are an important aspect of understanding dose-response relations for arsenic's action as a toxicant and a carcinogen.  In a study in Mexico, Dr. Miroslav Styblo from the University of North Carolina at Chapel and his colleagues are studying the characteristics of diabetes associated with chronic exposure to As in drinking water.  Their studies have characterized the diabetic state in this population and linked the capacity for arsenic metabolism to disease susceptibility.  In a study of arsenic-exposed populations in Bangladesh, Dr. Megan Hall of Columbia University and her colleagues are looking at relations between exposure to arsenic and changes in genomic methylation and redox status that may relate to disease susceptibility.  In a third talk, David Thomas of the U.S. Environmental Protection Agency will survey the current understanding of arsenic metabolism and examine the links between the metabolism of arsenic and its toxic and carcinogenic actions.


              In a related keynote address sponsored by the Division of Chemical Toxicology, Dr. Robert Kavlock, Director of the National Center for Computational Toxicology, U.S. Environmental Protection Agency, will discuss an approach to determine the potential hazards of many chemicals in commerce with a comprehensive high throughput screening program (ToxCast).  Since 2005, ToxCast has profiled 1000 chemicals of environmental interest across more than 600 biological endpoints using mainly protein and cell- based in vitro assays.  This information has been used to create databases and models that reflect biological pathways and disease outcomes.  Independent analysis of data is encouraged by the transparency of databases, results, and models.  The ToxCast effort is helping to transform the conduct of toxicology.