Tasnim Mokhtar

Please, help me

Discussion created by Tasnim Mokhtar on May 24, 2015
Latest reply on Jun 27, 2015 by Tasnim Mokhtar

I try to synthesis ethyl (2-benzyl-6-iodo-4-oxoquinazolin-3(4H)-yl)acetate by three ways:

1-  2-benzyl-6-iodoquinazolin-4(3H)-one was stirred and heated with ethyl chloro acetate and potassium carbonate anhydrous in dry acetone at 60 C for 24 hours

2-  2-benzyl-6-iodoquinazolin-4(3H)-one was stirred and heated with ethyl chloro acetate in dry pyridine for 3 hours.

3- 2 -benzyl-6-iodoquinazolin-4(3H)-one was stirred and heated with chloro acetic acid in 10% NaOH and ethanol for 3 hours.


Unfortunately, I can't obtain 2 -benzyl-6-iodoquinazolin-4(3H)-one

please, help me

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