Alex Dean

Applications of Deoxynivalenol

Discussion created by Alex Dean on Feb 24, 2018

Deoxynivalenol inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity. Hence, it's used as potent protein synthesis inhibitor. Besides,it exhibits cytotoxic activity in vivo via the ribotoxic stress responseand induces p38-mediated gene expression and apoptosis in leukocytes.