Name:
Jun Wu
Country:
China
City:
Guangzhou
State/Province:
ACS Member:
Local Section:
International Chapter:
Technical Division Membership:
Organic Chemistry Division
Technical Division Membership Emeritus:
Subdivision Member:
ACS Activities:
Company/Institution Name:
Career Stage:
Professional
Research and Special Interests:
Jun Wu, born on October 16, 1968, worked as a research professor studying marine natural products chemistry in Key Laboratory of Marine Bio-resourses Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China. He obtained his PhD degree of pharmacognosy from the School of Pharmaceutical Sciences, Peking University, where he studied the isolation, structure elucidation and structure-activity relationships of bioactive compounds from Traditional Chinese Medicine under the guidance of Professors Pengfei Tu and Yuying Zhao. Since 2001, he has worked as a scientist studied natural products of mangrove plants from south China at the South China Sea Institute of Oceanology, Chinese Academy of Sciences, where he is currently a professor, deputy director of the Guangdong Key Laboratory of Marine Materia Medica, and director of Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences. Since the September 2005, he has been a member of the Division of Organic Chemistry, American Chemical Society. And since the beginning of the year 2007, he has been a member of Special Interest Committee of Marine Drug, Chinese Pharmaceutical Association. He has been a visiting scholar to the Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-UniversitAt Dusseldorf, Germany. During his recent seven years of research on the secondary metabolites of mangrove and mangrove-associated plants, ten mangrove species, including Acanthus ilicifolius, Aegiceras corniculatum, Heritiera littoralis, and Xylocarpus granatum, have been phytochemically investigated by him or his research group, and about 200 compounds including 70 new ones have been isolated and characterized. He has published over 40 scientific papers about the chemistry of mangrove plants in international journals. He is the inventor of four patents and his current research interests focus around bioactive natural products from mangrove plants and marine unicellular algae. In the year 2004, he found an important type of organic compound, named phragmalin 8, 9, 30-ortho ester, from a Chinese mangrove plant Xylocarpus granatum and published this result in the famous international journal Organic Letters 2004, 6(11), 1841-1844. Recently, thirteen limonoids with a new carbon skeleton, named xylogranatins F-R, have been isolated from the seeds of a Chinese mangrove, Xylocarpus granatum, suggesting a new biogenetic pathway to tetranortriterpenoids. Among the above compounds, Xylogranatins F, G and R were found to exhibit marked antifeedant activity against the third instar larvae of Mythimna separata (Walker) at a concentration of 1 mg/mL. These results have been published in the famous international journal Chemistry-A European Journal 2008, 14, 1129-1141.
Area of Expertise:
marine natural products, mainly on mangrove plants and marine dinoflagellates
Years of Expertise:
6-10