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Selective Bromination on HEDTA, organic reaction

Hi Chemists,

I have general question, I am currently working HEDTA selective bromination on alcohol group but I have issuses in extracting, isolation and even analyzing the reaction by TLC because compound is only soluble in water at rt. So Please suggest me the exact reaction condition for TLC and product Isolation or literature on selective bromination in presence of acid and amine groups.

Immediate help is needed