Solvent Suitability for Acetonitrile as per ACS method_UHPLC & HPLC.docx
Anyone please help me in below issue.
Please find attached LC chromatograms of Solvent suitability of Acetonitrile solvent done as per ACS method on UHPLC and HPLC. I got the pattern as per attached chromatograms. So I need to understand why I got negative baseline in UHPLC when 100% ACN was running in programme. Kindly share standard chromatogram if available.