I recently published an ebook titled 'Paper-roll Chromatography/Electrophoresis which briefly explains how a paper roll of filter paper or any suitable substitute can be used for large scale separation of organic mixtures. This procedure could also be used to isolate and purify ionic organic substances such as amino acids and proteins.
It is envisaged that within the coming decade, a lot of natural products would be purified and identified on a large scale with consequential reduction in the cost of these substance. The procedure is cost effective.
However, these techniques still require automation in order to reduce the manual tasks of scientists.
The ebook can be sourced online through the web link below
https://www.smashwords.com/books/view/454490