Background: fluorine compounds have had a profound impact on the development of bioactive for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals prescribed or administered in the clinic contain a fluorine atom and 30% of the leading 30 blockbuster drugs by sales contain a fluorine.
Generally, fluorine chemistry service in the lab is about:
Synthesis of fluorinated compound using fluorinating agents, fluorinated building block, and in-situ generated HF
Teflon-coated 150-litter-vessel, with operating temperature from -100 to +70 Centigrade
Special equipment to handle F2, SF4, and HF
Design and Synthesis of F-templates/scaffolds and fluorinated reagents