Major types of SRPK
There are many SRPKs have been found, such as SRPK1. SRPK1 is an RNA splicing kinase with high specificity for serine/arginine rich domain (RS domain). And SRPK1 can identify arginine and phosphorylate the serine in the development of tumors, leading to the progression of tumors.
SRPIN340 is a specific inhibitor of SRPK, the IC 50 of which is 0.89 μM, and there is no significant inhibition of the other 140 kinds of kinases.