Alex Dean

Major types of SRPK inhibitor

Discussion created by Alex Dean on Aug 29, 2019

Major types of SRPK


There are many SRPKs have been found, such as SRPK1. SRPK1 is an RNA splicing kinase with high specificity for serine/arginine rich domain (RS domain). And SRPK1 can identify arginine and phosphorylate the serine in the development of tumors, leading to the progression of tumors.

SRPK inhibitor

SRPIN340 is a specific inhibitor of SRPK, the IC 50 of which is 0.89 μM, and there is no significant inhibition of the other 140 kinds of kinases.