Contributed by Christine Aurigemma, Pfizer, San Diego, CA, USA

The “Integration of Greener, Process-Friendly Approaches for Monitoring Reactions for Pharmaceutical End-Game Chemistry” session featured quality speakers from industry and academia, including the Chief Scientific Officer of a chemistry CRO, on a broad spectrum of topics from microfluidics to process analytics at the plant scale. These presentations touched on various green and sustainable tools and techniques for improving process control while reducing waste and were in alignment with the conference theme "Sustainable Production to Advance the Circular Economy."

By Anthony Maiorana, polymer chemist and writer of The Polymerist Newsletter

If we think about modern industrial chemistry, things really took off around the 1940s as steam cracking, catalytic cracking, and the use of synthetic materials started to become widespread. The widespread availability of refined oil at low costs over the last 60 years created less of a need for refining chemicals from biomass, but crude oil is inherently finite on a human time scale. Over the last few decades we have seen the growth of green chemistry and engineering principles in academia and the chemical industry for numerous reasons, but one of them is the potential future scarcity of oil as a chemical feedstock. If you are reading this then, it is likely through the ACS Green Chemistry Institute and I won’t get into the specifics of green chemistry principles, but I will attempt to write about the utilization of biomass in industrially relevant specialty polymers and plastics.

By Ian Mallov, research chemist at Inkbox Ink

When Virgin founder Sir Richard Branson offered $25 million for the invention of an efficient carbon sequestration technology in 2007, an Oregon environmentalist named Andy Kerr cheekily submitted a drawing of

Thanks to everyone who joined the ACS Green Chemistry Institute^® for the 25_th Annual Green Chemistry & Engineering (GC&E) Conference the week of June 14! The Conference Co-Chairs, Jillian Goldfarb at Cornell University and Guy Humphrey at Merck, did an amazing job organizing programming around the theme "Sustainable Production to Advance the Circular Economy". The success of the conference was due to the hard work of Jillian and Guy, the advisory committee, the symposium organizers, and my wonderful ACS colleagues in the Green Chemistry Institute and the Meetings Department.

By Aurora Ginzburg, Ph.D., Education Program Specialist, ACS Green Chemistry Institute; and Jennifer MacKellar, Program Manager, ACS Green Chemistry Institute

In 2015 and 2020, the ACS GCI surveyed ACS members in higher education to evaluate the status of

We are thrilled to celebrate the 25th anniversary of the Green Chemistry & Engineering Conference when conference attendees gather virtually next month!  The inaugural conference was organized in 1997 by the U.S. Environmental Protection Agency and remains the premier green chemistry and engineering conference in North America, attracting almost 5,000 attendees to last year’s virtual gathering.  The ACS Green Chemistry Institute is proud to organize this prestigious conference with the support of so many loyal sponsors every year.

Contributed by Dr. Michal Freedhoff, Principal Deputy Assistant Administrator for the Office of Chemical Safety and Pollution Prevention, U.S. Environmental Protection Agency

This year marks the 25th anniversary of the Green Chemistry Challenge Awards and it’s an opportunity to celebrate a quarter century of groundbreaking scientific solutions that have and will continue to make a positive impact on human health and the environment.

That’s why I’m looking forward to joining you at the Green Chemistry & Engineering Conference in June to present the 2021 Green Chemistry Challenge Awards on behalf of ACS and the U.S. Environmental Protection Agency (EPA). These awards are a wonderful way for us to recognize innovation by American businesses and researchers that have redesigned chemical products and processes to reduce or eliminate the use and manufacture of hazardous substances. These innovations help protect vulnerable communities, prevent pollution at its source, and keep U.S. businesses globally competitive by creating more sustainable products. 

Contributed by Samy Ponnusamy, Ph.D., Fellow & Global Manager – Green Chemistry, MilliporeSigma, St Louis, MO; Srinivasan Ambatipati, Ph.D., Assistant Professor & Coordinator of Chemical Engineering, McNeese State University, Lake Charles, LA

In this year’s GC&E Conference, we have organized a technical symposium on the topic “Design of Chemicals, Novel Chemistries, Synthetic Pathways & Processes that Enable a Circular, More Sustainable Economy”. Case studies will be presented to illustrate how industry and academia have successfully implemented novel design strategies to achieve a more circular and sustainable economy. The examples from the session will describe the design and approaches taken, the challenges faced and how a solution for the challenge was achieved. Also, this session will discuss the importance of implementing sustainability as a basic design criterion to successfully achieve a closed-loop economy.

By David A. Laviska, Assistant Professor at Seton Hall University and Sarah Prescott, Associate Professor at the University of New Hampshire, Manchester

It’s not uncommon for academics working in the sciences to feel a sense of isolation (no, this isn’t a reference to the COVID pandemic that has forced an extra measure of isolation on all of us). Depending on individual research interest(s) and prior training, it’s likely that most chemists feel some sense of “working in a vacuum”. How many of us are lucky enough to have close working colleagues who have expertise similar to our own? In most traditional academic settings, each scientist occupies a unique niche and this intellectual siloing can hinder the sharing of ideas and collaborative innovation, both in the research laboratory and in teaching. The latter can be especially challenging since major changes in the classroom (for gateway courses in particular!) tend to be much more broadly “visible” to all the stakeholders in higher education (students, fellow faculty, and administration).

The ACS Green Chemistry Institute (GCI) Pharmaceutical Roundtable honors the work of Stephen Dalby, Francois Levesque, Cecilia Bottecchia and Jonathan McMullen at Merck with the 2021 Peter J. Dunn Award for Green Chemistry & Engineering Impact in the Pharmaceutical Industry. The team’s innovation is titled, “Greener Manufacturing of Belzutifan (MK-6482) Featuring a Photo-Flow Bromination.”

Contributed by Natalie J. O’Neil, Higher Education Program Manager, Beyond Benign and Mevan Dissanayake, BE Planar PCD Regen Process Engineer at Intel Corporation

What comes to mind when you visualize your future green chemistry or engineering career? Is the term “Green” in your title? Did you find it based on the specific call out for those skills in the job posting? If you are searching for a position, you may be disappointed when limited or no search results appear with the terms “Green Chemistry” or “Green Engineering”. Does that mean these careers do not exist? No, they do—trust us! Many future careers in academia, industry, nonprofits and government agencies have an increasing priority placed on hiring students with the skills to design and apply safer, more sustainable chemicals, materials, products, and processes. Join us to learn how to leverage your green credentials in various career paths and hear how others have built a career under the umbrella of green chemistry and engineering.

Contributed by Natalie O’Neil, Higher Education Program Manager, Beyond Benign, David A. Laviska, Assistant Professor, Seton Hall University and Michael Wentzel, Associate Professor, Augsburg University

This fast-paced and engaging symposium at the 25th Annual Green Chemistry & Engineering (GC&E) Conference will provide educators of all levels (K-12, undergraduate, and graduate) with the opportunity to learn about innovations and initiatives for incorporating green chemistry content in lecture, laboratory, and outreach activities.

Contributed by Eric G. Moschetta (Center for Reaction Engineering - Process R&D, Abbvie Inc.), Benjamin Rizkin (Process Research & Development, Abbvie, Inc.), and Nick Uhlig (Process Development, Gilead Alberta ULC).

The ACS GCI Pharmaceutical Roundtable’s flow chemistry team has organized a symposium for this year’s Green Chemistry & Engineering Conference titled “Flow chemistry and continuous processing enabling sustainable chemical development and manufacturing”. This full-day session will include presentations on a broad range of topics with a common focus on process intensification, integrated multi-step processes, efficient use of materials and energy sources, and waste mitigation.

Contributed by Dr. Nimrat K. Obhi, Program Manager, Higher Education, Beyond Benign

It is essential that current and future scientists are able to understand and practice chemistry that supports good health and well-being. Additionally, it is critical that chemistry is used in ways that align with responsible consumption and production. Ensuring that we have this understanding of green chemistry helps us as a society better work towards the 17 key global Sustainable Development Goals outlined by the United Nations in 2015.

Contributed by Louis J. Diorazio, Chemical Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, United Kingdom

In the heat of scientific progress and corporate challenges, the role of solvents is often downplayed. It can be easy to assume that a solvent merely dissolves materials, indeed, awareness of solvents for the general public is generally restricted to situations such as cleaning a stain or grease with "a bit of solvent". 

Contributed by Drs. Deanna Scheff and Amie Norton, USDA Agricultural Research Service (ARS)

Promoting food security and reducing agricultural waste through new and innovative technologies is the topic of the session “Decreasing the Environmental Footprint by Decreasing Agriculture Waste” which we have organized for this year’s virtual GC&E Conference. This symposium brings together agricultural economists, chemists, engineers, and entomologists from around the world into one interactive symposium to talk about the science and technology behind reducing agricultural waste.

As spring arrives in the Northern Hemisphere and the vaccine rollout continues, there is much to be hopeful for in the year to come. This spring, it seems the seedlings of change in chemistry education, planted by many over the years, are also beginning to emerge. Here in the ACS Green Chemistry Institute (GCI), our vision of influencing the way students learn chemistry in the undergraduate gateway courses (general and organic chemistry) is taking shape.  Starting in January, we began working with 36 educators from across the U.S. and Canada to develop green and sustainable chemistry (GSC) modules for these courses. Seeing these modules take shape is inspiring and exciting!

Contributed by Joe Sagues, Assistant Professor, North Carolina State University, & Matteo Grattieri, Assistant Professor, University of Bari Aldo Moro

The ACS Green Chemistry Institute and iScience are sponsoring an exciting session at this year’s GC&E conference called “Electrosynthesis of Chemicals & Fuels”, which will showcase leaders in industry, academia, and national labs. This session will bring together experts from two distinct, yet highly related fields: 1) microbial electrosynthesis and 2) catalytic electrosynthesis. The intention of this session is to exploit exciting synergies that exist between these two research areas, and to foster collaborations and future research directions in this highly multidisciplinary field. The session will address multiple challenges present in the field of electrosynthesis. These challenges include, but are not limited to, 1) C-C bond formation for C2+ compounds, 2) electrochemical wiring of bacteria and high product selectivity, 3) energy efficient processes with low overpotentials, 4) improved mass transfer of gaseous substrates, and 4) techno-economic viability & commercialization. A diverse group of researchers will be speaking with backgrounds ranging from synthetic biology, electrochemistry, catalysis, and process engineering.

It has been a full year since most of us began working from home. The accelerated rollout of vaccines brings hope for an end to the pandemic in the near future.  In the meantime, we will continue to share our science through such virtual events as the ACS Spring 2021 National Meeting, April 5-30, and the Green Chemistry & Engineering Conference, June 14-18. 

By Aurora Ginzburg, Ph.D., Chemistry Education Program Specialist, ACS Green Chemistry Institute

I recently read the National Academies of Sciences, Engineering, and Medicine consensus report, How People Learn II (HPL2), and was struck by the many potential opportunities for education in green and sustainable chemistry to address the report’s findings on improving learning outcomes. Some of these opportunities are summarized below.

Dr. Jonathon Moir, Program Manager, GCTLC, Beyond Benign

My name is Dr. Jonathon Moir and I am thrilled to be writing to you today as the new Program Manager for the Green Chemistry Teaching and Learning Community (GCTLC). The GCTLC—an online platform set to launch in 2023—is a joint initiative announced in December by the ACS Green Chemistry Institute and Beyond Benign that will help revolutionize the way green chemistry educational resources are shared and further catalyze collaboration, networking and mentorship among educators, students, industry stakeholders and community members.

By Prof. Dr. Jun Huang, School of Chemical & Biomolecular Engineering, The University of Sydney, The University of Sydney Nano Institute

Q: What sparked your passion for chemistry and engineering?

A: The significance of chemical engineering for people’s lives. Chemical engineers developed 1) fertilizer production for higher agricultural productivity to feed huge populations; 2) pharmaceuticals for diseases; 3) clean fuels and energy storage for our daily life; 4) processes to provide clean water for drinking; 5) new technologies for waste disposal and recycling; and 6) greenhouse gas reduction technology for climate change. The progress and achievement of my work in chemical engineering can benefit our society and improve our quality of life, which attracts my passion for chemistry and engineering. 

This January, a group of motivated educators from across the U.S. and Canada began the process of creating education modules to integrate green and sustainable chemistry (GSC) into general and organic chemistry topics. The effort is part of the ACS GCI Educational Module Development Project—a three-year project aimed at providing the resources and training for undergraduate educators to accelerate the adoption of GSC in the classroom. Fifteen teams have been formed to work on 31+ modules covering topics like equilibrium, electrochemistry, chirality, and synthetic design from a green chemistry and systems thinking perspective. We checked in with one team—Prof. Marta Guron of Villanova University and Prof. Lihua Wang of Kettering University—to hear their vision for and experience with the project thus far.

By Gabriela Gastelu, Ph.D. student at the National University of Córdoba, Argentina, and 2021 Heh-Won Chang Fellow in Green Chemistry

I remember the first time I entered a laboratory as a secondary school student in my home city in Argentina. Its equipment was quite basic; however, I was delighted with all the glass material and the idea of making new things just by mixing components. Yes, I know my idea of a chemist at that time was really simple! But that simple idea inspired me to decide to study chemistry at the university.

By Isamir Martinez, Ph.D., PMP, Scientific Alliances & Business Engagement Manager, ACS Green Chemistry Institute; Stefan Koenig, Ph.D., Senior Scientist, Genentech; and, Ben I. Andrews, Investigator of Chemical Development, Product Development & Supply, GlaxoSmithKline

Aiming to employ oligonucleotides (ON), which are short deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules, as medical remedies has been a goal of scientists and physicians for some time.  As genetic information is carried forth from DNA through RNA, and eventually to the protein output via the central dogma of biology, there exist invaluable opportunities to address illness before it manifests itself. 

On January 1, the U.S. Senate passed the omnibus National Defense Authorization Act (NDAA). Within the NDAA Bill, Section E was the culmination of over 15 years of advocacy effort to deliver legislation that seeks to further the development of sustainable

By Aurora Ginzburg, Education Specialist, ACS Green Chemistry Institute

We are pleased to announce the student recipients of the 2021 ACS Green Chemistry Awards! Even with all the challenges that 2020 brought, there was a competitive field of applicants and the judges (external committees assembled by the ACS Green Chemistry Institute) were highly impressed!

By Aurora Ginzburg, Education Specialist, ACS Green Chemistry Institute

The U.N. reports that 2.2 billion people still lack safely managed drinking water and 1 in 4 health care facilities lacks basic services.  It’s been estimated that in 2015 alone 1.8 million deaths were caused by water pollution. The U.N. has designated targets within Sustainable Development Goal (SDG) 6, Clean Water and Sanitation, that aim to address these issues. These challenging, expansive issues resulting from a lack of or aging infrastructure, legacy chemical pollution, drought, and water rights issues will require different solutions depending on the region. There are issues of both water purity and access, and chemists are best equipped to address the challenge of purity. In particular, Targets 6.3 and 6.A necessitate chemistry technologies:

By Mary Kirchhoff, Ph.D., Director, ACS Green Chemistry Institute

In my last column, I reflected on the challenges we all faced in 2020, along with the unexpected opportunities presented by the pandemic.  As we wrap up the first month of 2021, I am optimistic that the new year will bring an increased focus on, and appreciation for, the role of green chemistry in achieving a sustainable future.

By Aurora Ginzburg, Education Specialist, ACS Green Chemistry Institute

This year the ACS Green Chemistry Institute selected 22 ACS Student Chapters to receive Green Chemistry Awards. Congratulations to all of the recipients! To qualify for this award, a chapter had to complete at least three green chemistry (GC) activities. These activities had to incorporate distinctly GC ideas like maximizing resource efficiency while reducing negative impacts on human/environmental health and safety.