The ACS Green Chemistry Institute (GCI) Pharmaceutical Roundtable honors the work of Stephen Dalby, Francois Levesque, Cecilia Bottecchia and Jonathan McMullen at Merck with the 2021 Peter J. Dunn Award for Green Chemistry & Engineering Impact in the Pharmaceutical Industry. The team’s innovation is titled, “Greener Manufacturing of Belzutifan (MK-6482) Featuring a Photo-Flow Bromination.”

Contributed by Louis J. Diorazio, Chemical Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, United Kingdom

In the heat of scientific progress and corporate challenges, the role of solvents is often downplayed. It can be easy to assume that a solvent merely dissolves materials, indeed, awareness of solvents for the general public is generally restricted to situations such as cleaning a stain or grease with "a bit of solvent". 

By Isamir Martinez, Ph.D., PMP, Scientific Alliances & Business Engagement Manager, ACS Green Chemistry Institute; Stefan Koenig, Ph.D., Senior Scientist, Genentech; and, Ben I. Andrews, Investigator of Chemical Development, Product Development & Supply, GlaxoSmithKline

Aiming to employ oligonucleotides (ON), which are short deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) molecules, as medical remedies has been a goal of scientists and physicians for some time.  As genetic information is carried forth from DNA through RNA, and eventually to the protein output via the central dogma of biology, there exist invaluable opportunities to address illness before it manifests itself. 

By David Constable, Science Director, ACS Green Chemistry Institute

I’ve always had a tendency to ask questions, it’s sort of how I’m made.  For those of you who have had children, you might surmise that I never got out of the one-question-leads-to-another

By Dr. Love-Ese Chile, Founder and Technical Director, Regenerative Waste Labs

Since the industrial revolution, scientists have been innovating at a faster rate than ever before. These scientific discoveries and disruptions have been miracles for some, br

 By David Constable Science Director, ACS Green Chemistry Institute

Over the past few months we’ve highlighted the U.N. Sustainable Development Goals (SDG), showing just a few of the many ways in which chemistry plays an enormous part in achieving the goa

The ACS Green Chemistry Institute® convened companies in the oil and gas industry at the annual ACS GCI Hydraulic Fracturing Roundtable recently to discuss greener chemicals and processes in hydraulic fracturing. Baker Hughes hosted the meeting at their W

By David Constable, Science Director, ACS Green Chemistry Institute

In 2013, members of the American Chemical Society Green Chemistry Institute (ACS GCI) Chemical Manufacturers Roundtable (ChMRT), conceived a project to identify how to fundamentally change

By Christiana Briddell, Sr. Communications Manager, ACS GCI; Jennifer MacKellar, Program Manager, ACS GCI; Marta Gmurczyk, Safety Portfolio Manager, ACS

Today’s environmental headlines are replete with sustainability topics from climate change to plastics

Representing the largest body of chemists in the world, the American Chemical Society has an important role to play in supporting its members and working with partners committed to addressing global sustainability challenges. In part two of this series, w

Dr. Bryony Core, Senior Technology Analyst at IDTechEx

We live in the age of plastic. Our lives have become so enmeshed with it that it is becoming impossible to avoid in day to day life. Its uses are myriad: saving lives in medical devices, reducing carbo

The American Chemical Society's Green Chemistry Institute (ACS GCI) was honored to partner with the U.S. Environmental Protection Agency to host the 2019 Green Chemistry Challenge Awards ceremony and reception at the EPA headquarters in Washington D.C. th

Contributed by Samy Ponnusamy, Fellow & Global Manager, Green Chemistry, MilliporeSigma

The 12 principles of green chemistry provide a conceptual framework for green chemistry that is globally accepted, which was an important starting point.  As the practi

Has the growing awareness of the reality and impacts of disposable plastic pollution finally started to change the marketplace? It seems that many factors are coming together to shift food packaging options away from plastic lately. Maybe this scenario ri

By Paul Richardson, Director, Oncology Chemistry, Pfizer and Juan Colberg, Senior Director within CRD, Pfizer

The ACS GCI Pharmaceutical Roundtable convened on October 9-10, 2018 at the Pfizer site in Groton, Connecticut for their fall meeting. With the va

By Mr. Philip Krook, Communications Officer, ChemSec

Last week I heard a word that I had never heard before. It was a term explaining a phenomenon that has skyrocketed in the last years. The word was uberization.

At the time, I could already guess the meani

By Louis Diorazio, Pharmaceutical Technology and Development, AstraZeneca

Solvents are commonplace chemicals across industry and academia.  In many cases, the bulk of the materials that chemists process are solvents with the ‘interesting stuff’ present onl

The non-agrarian among us may not know this, but petroleum-derived, non-biodegradable, effectively non-recyclable plastic mulch is used extensively in farms across America to control weeds, retain moisture in the soil, and increase crop yields.

My own expe

The Franklin Institute in Philadelphia, Pa. has announced it is seeking nominations for the 2019 Bower Award and Prize for Achievement in Science of individuals who have made significant contributions to green and sustainable chemistry. The prizewinner wi

Contributed by Jane Murray, Ph.D., Global Head of Green Chemistry, Merck KGaA, Darmstadt, Germany (MilliporeSigma)

Summary

Increasing the availability of safer, sustainable solvents is expected to significantly impact industrial Green Chemistry programs. Cy

Contributed by Max J. Hülsey, Ph.D. Candidate; Ning Yan, Assistant Professor, Department of Chemical and Biomolecular Engineering, National University of Singapore

The word ‘refinery’ evokes imagery of huge chemical plants spitting out steams and flames in

Professors Bruce Lipshutz, Ph.D., Professor of Chemistry and Biochemistry, University of California – Santa Barbara, and Sachin Handa, Ph.D., Assistant Professor of Chemistry at the University of Louisville, have been awarded the Peter J. Dunn Award for G

Despite the wide variety of chemistry conducted as part of drug discovery and development and the undoubted ingenuity of the chemists conducting the research, the majority of reactions still fall into a relatively small number of categories.

With this in m

Contributed by Samy Ponnusamy, Ph.D., Fellow, Green Chemistry, MilliporeSigma; and Jeffrey Whitford, Head of Corporate Responsibility and Branding, MilliporeSigma

Summary: MilliporeSigma created a unique, web-based greener alternative scoring matrix, also

Contributed by Juan Colberg, Green Chemistry Leader/Senior Director of Chemical Technology, Pfizer; Javier Magano, Principal Scientist, Pfizer; and John Wong, Research Fellow, Pfizer

2012 marked the 10-year anniversary of Pfizer’s Green Chemistry Program,

Drugs are expensive. That is something the whole world can agree on. People are spending too much on drugs and an unprecedented amount of population does not even have access to medications in the first place. Diminished access to drugs may stem from many

Contributed by Oleg Figovsky, Director of Research and Development, Hybrid Coating Technologies; and Alexander Leykin, Olga Birukova, Raisa Potashnikova, and Leonid Shapovalov, Polymate Ltd. International Nanotechnology Research Center

Non-isocyanate Hybri

Contributed by Jenna Jambeck, Ph.D., Associate Professor of Environmental Engineering, College of Engineering, and Director, Center of Focus for Circular Materials Management, New Materials Institute, University of Georgia; Mackenzie Carter, Graduate Rese

In 2004, the United States Department of Energy published a landmark report titled “Top Value Added Chemicals from Biomass,” in which they highlighted a dozen molecules as the most promising framework molecules that could potentially replace commonly used

Contributed by J. H. Docherty and S. P. Thomas, EaStCHEM School of Chemistry, University of Edinburgh

Chemical catalysis is an engine that powers modern society. The majority of modern chemical transformations, however, rely on the use of precious metals,